Biocanina pest control external Synergix Canis 20 to 40kg 4 Pipettes

Protects the big dog against fleas, ticks, sandflies and mosquitoes Learn more
Manufacturer: Biocanina


SKU 8150276 Biocanina Antiparasitaire Externe Synergix Grand Chien 20 40Kg 4 Pipettes


In dogs: use during infestations by fleas and/or ticks, when repellent activity (anti-gorgement) against sandflies or mosquitoes is also necessary. Fleas: Treatment and prevention of infestations by fleas (Ctenocephalides felis). Fleas on the dog are killed within 24 hours following the treatment. A single treatment has a persistent efficacy against new infestations by adult fleas for four weeks. The product may be incorporated into a strategy for treatment of dermatitis by allergy to the stings of chips (DAPP) when this condition has previously been diagnosed by a veterinarian. Tick: A single application provides persistent acaricidal efficacy against infestation by ticks (Ixodes ricinus, Dermacentor reticulatus and Rhipicephalus sanguineus) for four weeks. If ticks are present at the time of the application, they may not all be killed within 48 hours but be during the week. Sandflies and mosquitoes: A single treatment ensures a repellent activity (anti-gorgement) against sandflies (Phlebotomus perniciosus) and mosquito (Culex pipiens, Aedes aegypti) for four weeks. Fipronil is an insecticide and acaricide for the family of the phenylpyrazoles. Fipronil and its metabolite fipronil sulfone affect the chloride channel activated by ligands, in particular the gamma-aminobutyric acid neurotransmitter (GABA)-activated channels but also the desensitizing (D) and non-desensitizing (N) channels activated by glutamate (Glu, invertebrate-specific ligand-gated chloride channel). They thus block transfer pre - and postsynaptic chloride ions across the cell membrane. As a result, uncontrolled activity of the central nervous system and the death of insects or mites. Permethrin belongs to the family of I type pyrethroid insecticide activity, acaricidal and repellent. Pyrethroids affect vertebrates and invertebrates voltage-dependent sodium channels. Called "open channel blockers", they act on sodium channels in both slowing their activation and inactivation, which leads to a State of hyperexcitability and death of the parasite. The product exhibits insecticidal activity and acaricide flea (Ctenocephalides felis) and ticks (Rhipicephalus spp., Dermacentor spp., Ixodes ricinus), as well as a repellent activity (anti-gorgement) against sandflies (Phlebotomus perniciosus) and mosquitoes (Culex pipiens, Aedes aegypti). It has been shown experimentally that when it is applied on the dog at least two days before exposure to ticks, product indirectly reduces the risk of transmission of Babesia canis canis by infected ticks (Dermacentor reticulatus) up to 28 days after application. Reducing the risk of canine babesiosis in treated dogs.

directions for use:

Remove the pipette from the surblister. Keep it in a vertical position. Tap the narrow part of the pipette to ensure that the content is well down in the central part of the pipette. Break the autocassable end of the pipette for spot - on following the engraved line. Discard the hair of the animal until the skin is visible. Place the tip of the pipette directly on the exposed skin. Squeeze gently several times to completely empty the contents of the pipette in two to four points on the basis of the weight of the dog, along the back between the shoulders and the base of the tail. For dogs weighing less than 20 kg, apply the product in two points. For dogs of more than 20 kg, apply the product in 2-4 points.


A 4.4 ml pipette contains: Substance (s) active (s): Fipronil... 268,40 mg permethrin... 2398,00 mg Excipient (s): Butylhydroxyanisole (E320)... 0.88 mg butylated hydroxytoluene (E321)... 0.44 mg


2 2 4.4 ml pipettes blister box

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