Biocanina Milbetel Vermifuge Dog + 5kg 2 tablets
Biocanina Milbetel Vermifuge Chien + De 5Kg 2 Comprims
In dogs: treatment of mixed infestations by cestodes (flatworm) and nematodes (roundworms) adults of the following species: Cestodes: Dipylidium caninum Taenia spp.. Echinococcus spp.. Mesocestoides spp.. Nematodes: Ancylostoma caninum, Toxocara canis, Trichuris vulpis, Crenosoma vulpis (Reduction of the degree of infestation), Angiostrongylus vasorum (Reduction of the degree of infestation by parasites of the immature adult stages (L5) and adult. In cases where prevention of heartworm disease is useful and at the same time a treatment against tapeworms is necessary, the product can replace a monovalent product intended for the prevention of heartworm disease. For the treatment of Angiostrongylus vasorum infestations, administer 4 times of milbemycin oxime at an interval of one week. When concomitant treatment against tapeworms is indicated, it is recommended to administer once the product and then continue treatment during the three remaining weeks with monovalent product containing milbemycin oxime. In endemic areas, if concomitant treatment against tapeworms is indicated, an administration of the product every 4 weeks to prevent the angiostrongylose by reducing the parasitic load in immature adults (L5) and adults. Milbemycin oxime belongs to the Group of macrocyclic lactones produced by the fermentation of Streptomyces hygroscopicus var. aureolacrimosus. It is active against dust mites, the stages Larval and adult nematodes and larvae of Dirofilaria immitis. The activity of the milbemycin is related to its action on neurotransmission in invertebrates: milbemycin oxime, such as the avermectins and milbemycins, increases in nematodes and insects, the membrane permeability to the ions chloride via the glutamate-gated chloride channels (related to GABAA and glycine receptors in vertebrates). This results in hyperpolarization of the membrane of neuromuscular and flaccid paralysis and death of the parasite. Praziquantel is an isoquinoline pyrazino acetyl derivative. Praziquantel is active against cestodes and trematodes. It alters the membrane permeability to calcium (Ca2 + influx) the parasite, which causes an imbalance of membrane structures and leads to membrane depolarization to muscle contractions (cramps) virtually instantaneous and quick vacuolization of the syncytium integumentary, responsible for the decomposition of the integument (blisters). This facilitates the elimination in the gastrointestinal tract or led to the death of the parasite.
directions for use:
Oral. Recommended minimum dose: 0.5 mg of milbemycin oxime, and 5 mg of praziquantel per kg of body weight, administered as a single dose orally. The product should be administered during or after the meal. The tablets are flavored with meat and are easy to administer (usually dogs and puppies accept to take voluntarily, even without food).
Film-coated tablet contains: Substance (s) active (s): Milbemycin oxime... 12.5 mg Praziquantel... 125.0 mg Excipients: kernel microcrystalline Croscarmellose sodium Lactose monohydrate starch, pregelatinized starch Povidone Stearate, magnesium silica colloidal anhydrous filming natural flavour of liver of poultry Hypromellose microcrystalline cellulose Stearate macrogol
Box of 1 or 2 blister packs of 2 scored film coated tablet